SMTP 421 Service Not Available vs 550 Mailbox Not Found
SMTP 421 (Service Not Available) is a 4xx Transient Negative response, while 550 (Mailbox Not Found) is a 5xx Permanent Negative response. 421 indicates that the SMTP service is not available and the server is closing the transmission channel. This may be sent as a greeting or during a session if the server needs to shut down. In contrast, 550 means that the requested action was not taken because the mailbox does not exist or the recipient address is rejected by policy. This is a permanent failure indicating the address is invalid or blocked.
Description
The SMTP service is not available and the server is closing the transmission channel. This may be sent as a greeting or during a session if the server needs to shut down.
Quand vous le voyez
When connecting to a mail server that is overloaded, undergoing maintenance, or shutting down. The server cannot handle your request right now.
Comment résoudre
Retry the connection after a delay. If the issue persists, check server status and resources (CPU, memory, disk). Rate limiting or greylisting may also trigger this response.
Description
The requested action was not taken because the mailbox does not exist or the recipient address is rejected by policy. This is a permanent failure indicating the address is invalid or blocked.
Quand vous le voyez
When sending to an email address that does not exist on the destination server, or when the server's policy rejects your message (e.g., anti-spam, sender verification failure).
Comment résoudre
Verify the recipient's email address for typos. If the address is correct, the mailbox may have been deleted or your domain may be blocked — check your sender reputation and SPF/DKIM/DMARC records.
Différences clés
421 is a 4xx Transient Negative response, while 550 is a 5xx Permanent Negative response.
SMTP 421: The SMTP service is not available and the server is closing the transmission channel. This may be sent as a greeting or during a session if the server needs to shut down.
SMTP 550: The requested action was not taken because the mailbox does not exist or the recipient address is rejected by policy. This is a permanent failure indicating the address is invalid or blocked.
You encounter 421 when when connecting to a mail server that is overloaded, undergoing maintenance, or shutting down. The server cannot handle your request right now.
You encounter 550 when when sending to an email address that does not exist on the destination server, or when the server's policy rejects your message (e.g., anti-spam, sender verification failure).
Quand utiliser lequel
For 421 (Service Not Available): Retry the connection after a delay. If the issue persists, check server status and resources (CPU, memory, disk). Rate limiting or greylisting may also trigger this response. For 550 (Mailbox Not Found): Verify the recipient's email address for typos. If the address is correct, the mailbox may have been deleted or your domain may be blocked — check your sender reputation and SPF/DKIM/DMARC records.